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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2D
All Species:
4.55
Human Site:
S258
Identified Species:
8.33
UniProt:
Q14814
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14814
NP_005911.1
521
55938
S258
S
P
P
P
P
T
H
S
T
Q
L
G
A
P
S
Chimpanzee
Pan troglodytes
XP_001165500
521
55889
S258
S
P
P
P
P
T
H
S
T
Q
L
G
A
P
S
Rhesus Macaque
Macaca mulatta
XP_001103222
500
53974
G256
K
S
P
P
P
P
G
G
G
N
L
G
M
N
S
Dog
Lupus familis
XP_547534
525
56508
A258
L
G
G
E
L
N
S
A
N
G
A
C
P
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q63943
514
54974
N258
S
P
P
P
P
T
H
N
T
Q
L
G
A
P
S
Rat
Rattus norvegicus
O89038
507
54350
N258
S
P
P
P
P
T
H
N
T
Q
L
G
A
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507540
505
54598
G258
T
K
S
P
P
P
P
G
G
G
N
L
G
M
N
Chicken
Gallus gallus
Q9W6U8
499
53650
G260
K
S
P
P
P
P
G
G
G
G
L
G
M
N
N
Frog
Xenopus laevis
Q03413
498
54053
N258
S
P
P
S
P
N
Q
N
S
Q
L
G
A
N
S
Zebra Danio
Brachydanio rerio
NP_571392
529
57466
M258
P
P
P
P
S
T
Q
M
A
N
S
R
K
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
P258
P
P
T
I
A
P
I
P
P
N
M
S
A
P
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
D40
R
E
L
S
V
L
C
D
A
E
V
A
V
I
V
Baker's Yeast
Sacchar. cerevisiae
Q12224
676
73465
I258
F
N
G
R
P
P
P
I
S
I
S
P
N
K
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
53.7
72.5
N.A.
96.1
94.4
N.A.
54.1
54.7
73.6
70.1
N.A.
28
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
63.9
75.8
N.A.
97.1
95.5
N.A.
64.8
64.3
82.5
78.2
N.A.
39.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
40
0
N.A.
93.3
93.3
N.A.
13.3
33.3
60
33.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
6.6
N.A.
100
100
N.A.
26.6
40
73.3
33.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.2
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.9
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
16
0
8
8
47
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
16
% D
% Glu:
0
8
0
8
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
8
16
0
0
0
16
24
24
24
0
54
8
0
0
% G
% His:
0
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
8
0
8
0
0
0
8
0
% I
% Lys:
16
8
0
0
0
0
0
0
0
0
0
0
8
8
0
% K
% Leu:
8
0
8
0
8
8
0
0
0
0
54
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
8
0
16
8
0
% M
% Asn:
0
8
0
0
0
16
0
24
8
24
8
0
8
24
16
% N
% Pro:
16
54
62
62
70
39
16
8
8
0
0
8
8
47
8
% P
% Gln:
0
0
0
0
0
0
16
0
0
39
0
0
0
0
0
% Q
% Arg:
8
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
39
16
8
16
8
0
8
16
16
0
16
8
0
8
47
% S
% Thr:
8
0
8
0
0
39
0
0
31
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _